Background: In Switzerland, non-medical right-to-die organisations such as Exit Deutsche Schweiz and Dignitas offer suicide assistance to members suffering from incurable diseases. Objectives: First, to determine whether differences exist between the members who received assistance in suicide from Exit Deutsche Schweiz and Dignitas. Second, to investigate whether the practices of Exit Deutsche Schweiz have changed since the 1990s. Methods: This study analysed all cases of assisted suicide facilitated by Exit Deutsche Schweiz (E) and Dignitas (D) between 2001 and 2004 and (...) investigated by the University of Zurich’s Institute of Legal Medicine (E: n = 147; D: n = 274, total: 421). Furthermore, data from the Exit Deutsche Schweiz study which investigated all cases of assisted suicide during the period 1990–2000 (n = 149) were compared with the data of the present study. Results: More women than men were assisted in both organisations (D: 64%; E: 65%). Dignitas provided more assistance to non-residents (D: 91%; E: 3%; p = 0.000), younger persons (mean age in years (SD): D: 64.5 (14.1); E: 76.6 (13.3); p = 0.001), and people suffering from fatal diseases such as multiple sclerosis and amyotrophic lateral sclerosis (D: 79%; E: 67%; p = 0.013). Lethal medications were more often taken orally in cases assisted by Dignitas (D: 91%; E: 76%; p = 0.000). The number of women and the proportion of older people suffering from non-fatal diseases among suicides assisted by Exit Deutsche Schweiz has increased since the 1990s (women: 52% to 65%, p = 0.031; mean age in years (SD): 69.3 (17.0) to 76.9 (13.3), p = 0.000), non-fatal diseases: 22% to 34%, p = 0.026). Conclusions: Weariness of life rather than a fatal or hopeless medical condition may be a more common reason for older members of Exit Deutsche Schweiz to commit suicide. The strong over-representation of women in both Exit Deutsche Schweiz and Dignitas suicides is an important phenomenon so far largely overlooked and in need of further study. (shrink)

Background: In Switzerland, non-medical right-to-die organisations such as Exit Deutsche Schweiz and Dignitas offer suicide assistance to members suffering from incurable diseases.Objectives: First, to determine whether differences exist between the members who received assistance in suicide from Exit Deutsche Schweiz and Dignitas. Second, to investigate whether the practices of Exit Deutsche Schweiz have changed since the 1990s.Methods: This study analysed all cases of assisted suicide facilitated by Exit Deutsche Schweiz and Dignitas between 2001 and 2004 and investigated by the University (...) of Zurich’s Institute of Legal Medicine. Furthermore, data from the Exit Deutsche Schweiz study which investigated all cases of assisted suicide during the period 1990–2000 were compared with the data of the present study.Results: More women than men were assisted in both organisations. Dignitas provided more assistance to non-residents, younger persons : D: 64.5 ; E: 76.6 ; p = 0.001), and people suffering from fatal diseases such as multiple sclerosis and amyotrophic lateral sclerosis. Lethal medications were more often taken orally in cases assisted by Dignitas. The number of women and the proportion of older people suffering from non-fatal diseases among suicides assisted by Exit Deutsche Schweiz has increased since the 1990s : 69.3 to 76.9, p = 0.000), non-fatal diseases: 22% to 34%, p = 0.026).Conclusions: Weariness of life rather than a fatal or hopeless medical condition may be a more common reason for older members of Exit Deutsche Schweiz to commit suicide. The strong over-representation of women in both Exit Deutsche Schweiz and Dignitas suicides is an important phenomenon so far largely overlooked and in need of further study. (shrink)

Two right-to-die organisations offer assisted suicide in Switzerland. The specific legal situation allows assistance to Swiss and foreign citizens. Both organisations require a report of the person’s health status before considering assistance. This qualitative study explored these reports filed to legal authorities after the deaths of individuals in the area of Zurich. Health status reports in the legal medical dossiers of the deceased were analysed using content analysis and Grounded Theory. From 421 cases of assisted suicide (2001–2004), 350 reports on (...) health status were filed. Many cases contained diagnosis lists only. Other reports had more elaborate reports revealing that some physicians were aware about the patient’s death wish and the intention to solicit assisted suicide. Physicians’ attitudes ranged from neutral to rather depreciative. Few physicians openly referred the patient to the organisations and supported the patient’s request by highlighting a history of suffering as well as reporting understanding and agreement with the patient’s wish to hasten death. In the health status reports five categories could be identified. Some files revealed that physicians were aware of the death wish. The knowledge and recognition of the patient’s death wish varied from no apparent awareness to strongly supportive. This variety might be due to difficulties to discuss the death wish with patients, but might also reflect the challenge to avoid legal prosecution in the country of origin. To require comparable health status reports as requirements for the right-to-die organisations might be difficult to pursue. (shrink)

The focus on translational research in clinical trials has the potential to generate clinically relevant genetic data that could have importance to patients. This raises challenging questions about communicating relevant genetic research results to individual patients. An exploratory pharmacogenetic analysis was conducted in the international ovarian cancer phase III trial, AGO-OVAR 16, which found that patients with clinically important germ-line BRCA1/2 mutations had improved progression-free survival prognosis. Mechanisms to communicate BRCA results were evaluated, because these findings may be beneficial to (...) patients and their families. Communicating individual BRCA results was not anticipated during clinical trial design. Consequently, options were not available for patients to indicate their preference for receiving their individual results when they signed pharmacogenetic informed consent. Differences in local requirements, clinical practice, and opinion regarding the ethical aspects of how to convey genetic results to patients are all potential barriers to returning individual BRCA results to patients. Communicating the aggregate BRCA result from this study provided clinical investigators with a mechanism to disseminate the overall study finding to patients while taking individual circumstances, local guidelines and clinical practice into account. This study illustrates the importance of increasing the clarity and scope of informed consent and the need for patient engagement to ensure clinical trial participants can indicate their preference regarding receipt of potentially important individual pharmacogenetic results. This study was registered in the NCT Clinical Trial Registry under NCT00866697 on March 19, 2009, following approval from participating ethics committees. (shrink)

Розкрито сутність поняття «рейтинг». Доведено значущість рейтингової оцінки для суб’єктів фінансового ринку, зокрема для страхових компаній, потенційних страхувальників, інвесторів та кредиторів.

Name der Zeitschrift: Naharaim Jahrgang: 9 Heft: 1-2 Seiten: 4-24.

From the early 1790s until after the turn of the century, a very productive but also controversial exchange took place between Reinhold and Fichte. Though many key aspects of post-Kantian philosophy were discussed, the philosophical confrontation between Reinhold and Fichte is most instructive for the understanding of post-Kantian philosophy. The exchange started when Fichte published his verdict on Reinhold's Elementarphilosophie and disapproved of its fundamental principle. In 1794 Fichte challenged Reinhold by presenting his Wissenschaftslehre. Reinhold was not convinced of Fichte's (...) foundation of philosophy at first, but announced that he accepted the Wissenschaftslehre in 1797. While Reinhold and Fichte officially collaborated in the following three years, tensions concerning fundamental questions were still present. When Reinhold adopted Rational Realism, his relation to Fichte deteriorated and the exchange between the two finally ended. The contributions in the present collection focus on the central systematic issues at the different stages of the confrontation between Fichte and Reinhold, thereby illuminating questions that are essential to the understanding of the evolution of post-Kantian German philosophy. (shrink)

"Williams's masterful translation satisfies (at last!) a long-standing need. There are lots of good translations of Augustine's great work, but until now we have been forced to choose between those that strive to replicate in English something of the majesty and beauty of Augustine's Latin style and those that opt instead to convey the careful precision of his philosophical terminology and argumentation. Finally, Williams has succeeded in capturing both sides of Augustine's mind in a richly evocative, impeccably reliable, elegantly readable (...) presentation of one of the most impressive achievements in Western thought--Augustine's Confessions." --Scott MacDonald, Professor of Philosophy and Norma K. Regan Professor in Christian Studies, Cornell University. (shrink)

Ding und Begriff stellen den Kern von Peter F. Strawsons Philosophie dar: Worauf beziehen wir uns in unserem alltaglichen Denken und Sprechen und unter welchen Bedingungen konnen wir uns darauf beziehen? Mit dieser Frage, wie wir die Welt begrifflich erfassen, sind eine Reihe von Problemstellungen metaphysisch-ontologischer, epistemologischer, logischer und sprachphilosophischer Natur verbunden. An sie knupfen die hier versammelten Beitrage an. Die systematische Auseinandersetzung mit Strawsons Themen zeigt einige Schwachen seiner Positionen auf, weist aber auch Wege zu moglichen Losungen und bettet (...) Strawsons Philosophieren dadurch in aktuelle Debatten ein.". (shrink)

R.I.G Hughes offers the first detailed and accessible analysis of the Hilbert-space models used in quantum theory and explains why they are so successful.

There is sufficient evidence to believe that variations in the error-related negativity (ERN) are linked to dispositional characteristics in individuals. However, explanations of individual differences in the amplitude of the ERN cannot be derived from functional theories of the ERN. The ERN has a counterpart that occurs after correct responses (correct-response negativity, CRN). Based on the assumption that ERN and CRN reflect an identical cognitive process, variations in CRN might be associated with dispositional characteristics as well. Higher CRN amplitudes have (...) been found to reflect task engagement. In the present study, a simple-choice-reaction task was used to investigate ERN and CRN amplitudes in relation to their score on a conscientiousness scale. The task consisted of a simple rule that required pressing the left or right key when a circle or square appeared, respectively. During alternative conditions that occur infrequently, participants were instructed to violate or reverse the previously established response rules. Smaller ΔERN amplitudes (manifested in almost equal CRN and ERN amplitudes) and a tendency of better task performance from participants scoring high on the conscientiousness scale might indicate a greater focus on the task and higher motivation of responding correctly. In addition, higher Pc amplitudes directly following the CRN indicated that the response monitoring system of less conscientious participants showed a higher disengagement. The role of individual differences in CRN amplitude should be studied in future experiments on performance monitoring. (shrink)

In the first paragraph of the Grundlage der gesammten Wissenschaftslehre Fichte gives an extended exposition of his first principle. The aim of the article is to show that, first, this exposition is in fact an argument in favour of the first principle of the Wissenschaftslehre, and, second, that it answers the central point of the sceptical criticism put forward by Jacobi, Maimon and Schulze against Kantian philosophy. In order to corroborate these theses, the central point of the sceptical critique has (...) to be identified in a first step. Next, I examine Fichte’s strategy to meet the sceptical challenge. As a result, only a pre-systematic form of argument is adequate for Fichte to establish a principle that is immune to sceptical doubts, and, therefore, is a suitable starting point for a transcendental deduction. Finally, Fichte’s argument against the sceptics can be reconstructed in the following way: He takes up the central point of the sceptical critique and reformulates it as a criterion for a first principle. He then shows that the criterion is fulfilled by the I, if it is conceived in his own way, i.e. as pure activity.Fichte entwickelt im ersten Paragraphen der Grundlage der gesammten Wissenschaftslehre eine ausführliche Exposition seines ersten Grundsatzes. Der Beitrag hat zum Ziel zu zeigen, dass diese Exposition ein Argument für das erste Prinzip der Wissenschaftslehre darstellt und dass es ein Argument gegen den zentralen Punkt der skeptischen Kritik an der Transzendentalphilosophie, wie sie Jacobi, Maimon und Schulze formulierten, ist. Um diese Thesen zu untermauern, wird in einem ersten Schritt der zentrale Punkt der skeptischen Kritik identifiziert. Dem folgt eine Untersuchung der Strategie, mit der Fichte der Kritik begegnet, wobei sich eine vorsystematische Argumentation als geeignet erweist, einen ersten Grundsatz aufzustellen, der gegen die vorgebrachten Zweifel resistent und daher als Basis einer transzendentalen Deduktion tauglich ist. Fichtes Argumentation gegen den Skeptizismus kann dann folgendermaßen rekonstruiert werden: Fichte nimmt den zentralen Punkt der skeptischen Kritik auf und formt ihn in ein Kriterium für ein erstes Prinzip um. Er kann dann zeigen, dass das Ich das Kriterium erfüllt, sofern es als reine Tätigkeit aufgefasst wird. (shrink)

The capability of logical systems to express their own satisfaction relation is a key issue in mathematical logic. Our notion of self definability is based on encodings of pairs of the type (structure, formula) into single structures wherein the two components can be clearly distinguished. Hence, the ambiguity between structures and formulas, forming the basis for many classical results, is avoided. We restrict ourselves to countable, regular, logics over finite vocabularies. Our main theorem states that self definability, in this framework, (...) is equivalent to the existence of complete problems under quantifier free reductions. Whereas this holds true for arbitrary structures, we focus on examples from Finite Model Theory. Here, the theorem sheds a new light on nesting hierarchies for certain generalized quantifiers. They can be interpreted as failure of self definability in the according extensions of first order logic. As a further application we study the possibility of the existence of recursive logics for PTIME. We restate a result of Dawar concluding from recursive logics to complete problems. We show that for the model checking Turing machines associated with a recursive logic, it makes no difference whether or not they may use built in clocks. (shrink)

Concluding the deduction of imagination in § 4 of the Grundlage der gesammten Wissenschaftslehre, Fichte remarks that one lesson of the Wissenschaftslehre is that all reality is a product of imagination. One of the greatest thinkers of the age, Fichte writes, is teaching the same, but calls it a deception of imagination. Fichte’s remark is aimed at Salomon Maimon, and it shows that his deduction shouldn’t be read only as part of the systematic development of the theoretical Wissenschaftslehre, but should (...) also be considered as an argument against a specific kind of scepticism. In order to examine this overlooked anti-sceptical aim in the first Wissenschaftslehre, an overview of the deduction of § 4 with a focus on the systematic role of imagination will first be given. Second, Maimon’s sceptical argument against transcendental philosophy will be explained. In the centre again will stand Maimon’s Humean concept of imagination. Finally, it will be shown in which sense Fichte’s deduction of imagination has to be taken in order to be an adequate response to Maimonian scepticism.An die Deduktion der Einbildungskraft in § 4 der Grundlage der gesammten Wissenschaftslehre schließt Fichte die Bemerkung an, es werde hier gelehrt, dass alle Realität durch die Einbildungskraft hervorgebracht wird. Einer der größten Denker des Zeitalters – gemeint ist Salomon Maimon – lehre das Gleiche, nur nenne er es eine Täuschung durch die Einbildungskraft. Diese Bemerkung lässt erkennen, dass die Deduktion der Einbildungskraft nicht nur im Dienst der Entwicklung des theoretischen Teils der Wissenschaftslehre steht, sondern dass sie auch im Sinne eines antiskeptischen Arguments verstanden werden muss. Um diesen Aspekt von Fichtes Konzeption der Einbildungskraft genauer zu beleuchten, wird erstens die Deduktion in § 4 mit Blick auf die systematische Rolle der Einbildungskraft dargestellt. Zweitens wird Maimons skeptisches Argument gegen die Transzendentalphilosophie präzisiert, auf das sich Fichte mit seiner Äußerung bezieht, wobei Maimons sich an Hume orientierendes Verständnis der Einbildungskraft im Zentrum steht. Zuletzt wird geprüft, in welchem Sinn Fichtes Deduktion der Einbildungskraft als Antwort auf Maimons Skeptizismus verstanden werden muss. (shrink)

In 1791 Karl Leonhard Reinhold expressed full agreement with Kant’s verdict that appeal to common understanding is not acceptable in philosophy. Only three years later Reinhold presented a philosophical methodology in which common understanding was explicitly assigned an essential function. In my contribution, I shall first reconstruct Reinhold’s account of the relation between common understanding and philosophising reason (Section 2). According to this account, common understanding is supposed to provide a multitude of empirical facts of consciousness. Philosophising reason takes these (...) facts as the starting point of philosophical analysis and establishes their a priori, transcendental grounds. Common understanding and philosophising reason thus fulfil complementary roles: philosophy analyses, explains, and justifies the basic beliefs of common understanding; philosophical claims are, in turn, substantiated through their reference to the facts provided by common understanding. I shall also show that the account of the relation between common understanding and philosophising reason enables Reinhold to deal with some objections against his philosophical system. The appeal to common understanding thus serves the purpose of corroborating the structure and the contents of the Elementarphilosophie. In Section 3, I shall suggest that Reinhold’s introduction of common understanding was not influenced by common-sense philosophy but rather by the Wolffian conception of the relation between common cognition and philosophical cognition. Reinhold accepted the general outline of Wolff’s rationalist conception but adopted it to the framework of critical philosophy. In my concluding remarks (Section 4) I shall briefly indicate that the main characteristics of the account of the relation between common understanding and philosophical reason withstood Reinhold’s later changes of philosophical systems. (shrink)

This book offers a critical introduction to the work of American philosopher D. G. Leahy (1937-2014). Leahy's fundamental thinking can be characterized as an absolute creativity in which all creating is 'live' -- a happening occurring now that manifests a supersaturated polyontological actuality that is essentially created by the logic that characterizes it. Leahy leaves behind the categorial presuppositions of modern thought, eclipsing both Cartesian and Hegelian subjectivities and introducing instead an essentially new form of thinking founded in a nondual (...) logic of creation. The new thinking delineates the absolute unicity of existence as a creative interactivity beyond all traditional dichotomies (such as one vs. many, unity vs. plurality, identity vs. change): a fully "digitized" actuality that is nothing but newness, which inherently implies nothing but change. Through this new form of thinking, change itself is revealed to be the very essence of reality and mind. Any reader looking for a quantum leap beyond the thrall of modern and postmodern fixations is invited to hear and apprehend this new thinking that refuses to be conditioned by paradigms, categories, species, genera, walls, bridges, boundaries, or abstractions: an essentially free thinking that embodies creative novelty itself. (shrink)

In this first paperback edition, a new introduction by Tom Burke establishes the ongoing importance of Sleeper's analysis of the integrity of Dewey's work and ...

This book is not a study of Plato's philosophy, but a contribution to the literary interpretation of the dialogues, through analysis of their formal structure, ...

Linking the process of rational decision making to emotions, an award-winning scientist who has done extensive research with brain-damaged patients notes the dependence of thought processes on feelings and the body's survival-oriented regulators. 50,000 first printing.

Political liberals ask citizens not to appeal to certain considerations, including religious and philosophical convictions, in political deliberation. We argue that political liberals must include a demanding requirement of intellectual modesty in their ideal of citizenship in order to motivate this deliberative restraint. The requirement calls on each citizen to believe that the best reasoners disagree about the considerations that she is barred from appealing to. Along the way, we clarify how requirements of intellectual modesty relate to moral reasons for (...) deliberative restraint. And we argue against attempts to weaken our requirement of intellectual modesty by emphasizing those moral reasons. (shrink)

Many philosophers believe that there is a causal condition on perception, and that this condition is a conceptual truth about perception. A highly influential argument for this claim is based on intuitive responses to Gricean style thought experiments. Do the folk share the intuitions of philosophers? Roberts et al. (2016) presented participants with two kinds of cases: Blocker cases (similar to Grice’s case involving a mirror and a pillar) and Non-Blocker cases (similar to Grice’s case involving a clock and brain (...) stimulation). They found that a substantial minority agreed that seeing occurs in the Non-Blocker cases, and that in the Blocker cases significantly less agreed that seeing occurs. They thus hypothesized that folk intuitions better align with a no blocker condition than with a causal condition. This paper continues this line of enquiry with two new experiments. The paper investigates the generality and robustness of Roberts et al.’s findings by expanding the sense modalities tested from only vision to audition and olfaction as well. The paper also uses Gricean style thought experiments as a case study for investigating the “reflection defense” against the negative project in experimental philosophy. Our results replicate and extend Roberts et al.’s study and support their hypothesis that folk intuitions better align with a no blocker condition. They also provide an empirical reason to doubt the reflection defense. (shrink)

The author demonstrates that certain forms of irrationality - incontinent action and self-deception - which many philosophers have rejected as being logically or psychologically impossible, are indeed possible.

The Hellenistic philosophers and schools of philosophy are emerging from the shadow of Plato and Aristotle and are increasingly studied for their intrinsic philosophical value. They are not only interesting in their own right, but also form the intellectual background of the late Roman Republic. This study gives a comprehensive and readable account of the principal doctrines of the Stoics, Epicureans and various sceptical traditions from the death of Alexander the Great in 323 B.C. to around 200 A.D. Discussions are (...) arranged topically in order to address underlying issues and to make clear what the different schools have in common and how they differ. At the same time the coherence of each system as a whole is emphasized. (shrink)

Determining what has gone wrong in a malfunctioning body and proposing an effective treatment requires expertise. Since antiquity, philosophers and doctors have wondered what sort of knowledge this expertise involves, and whether and how it can warrant its conclusions. Few people were as qualified to deal with these questions as Galen of Pergamum. A practising doctor with a keen interest in logic and natural science, he devoted much of his enormous literary output to the task of putting medicine on firm (...) methodological grounds. At the same time he reflected on philosophical issues entailed by this project, such as the nature of experience, its relation to reason, the criteria of truth, and the methods of justification. This volume explores Galen's contributions to epistemology, as they arise in the specific inquiries and polemics of his works, as well as their legacy in the Islamic world. (shrink)